Moderate evidence from a systematic review indicates that when stearic acid is substituted for other saturated fatty acids (SFA) or trans fatty acids, plasma LDL cholesterol (LDL-C) levels are decreased; when substituted for carbohydrates, LDL-C levels are unchanged; and when substituted for monounsaturated fatty acids (MUFA) or polyunsaturated fatty acids (PUFA), LDL-C levels are increased. Therefore, the impact of stearic acid replacement of other energy sources is variable regarding LDL-C, and the potential impact of changes in stearic acid intake on cardiovascular disease risk remains unclear.
Moderate
Overall strength of the available supporting evidence: Strong; Moderate; Limited; Expert Opinion Only; Grade not assignable.
What is the association between dietary stearic acid LDL cholesterol? (DGAC 2010)
