Search Plan and Results
What is the relationship between alcohol intake and bone health? (DGAC 2010)
- January 1, 1995 through June 9, 2009
- Human subjects
- English language
- Sample size: Minimum of 10 subjects per study arm; preference for larger sizes, if available
- Dropout rate: Less than 20%; preference for smaller dropout rates
- Ages: Adults: Adults of legal drinking age (21 and older)
- Populations: Healthy, those with elevated chronic disease risk, those diagnosed with the highly prevalent chronic diseases (CHD/CVD, Hypertension, Type 2 DM, Osteoporosis, Osteopenia and Obesity) and those with breast cancer, colon cancer and/or prostate cancer.
Medical treatment or therapy
Diseased subjects (exceptions noted)
Malnourished and third-world populations or disease incidence not relative to US population, e.g. malaria
In vitro studies
Articles not peer reviewed (websites, magazine articles, Federal reports, etc.)
Cross-sectional study design.
Search Terms: Search Vocabulary
("Ethanol"[Mesh] OR “Alcohol Drinking”[mesh] OR "Alcoholic Beverages"[Mesh]) AND ("Bone Density"[Mesh] OR "Fractures, Bone"[Mesh] OR "Bone Diseases"[Mesh])
Total hits from all electronic database searches: 132
Total articles identified to review from electronic databases: 21
Number of Primary Articles Identified: 0
Number of Review Articles Identified: 1
Total Number of Articles Identified: 1
Number of Articles Reviewed but Excluded: 20
Berg KM, Kunins HV, Jackson JL, Nahvi S, Chaudhry A, Harris KA Jr, Malik R, Arnsten JH. Association between alcohol consumption and both osteoporotic fracture and bone density. Am J Med. 2008 May; 121 (5): 406-418. Review. PubMed PMID: 18456037; PubMed Central PMCID: PMC2692368.