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What impact has mandatory folic acid fortification had on the incidence of neural tube defect in the US and Canada? (DGAC 2010)Conclusion
Strong and consistent evidence demonstrates a large reduction in the incidence of neural tube defects (NTDs) in the US and Canada following mandatory folic acid fortification. Grade: Strong Overall strength of the available supporting evidence: Strong; Moderate; Limited; Expert Opinion Only; Grade not assignable
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